University of California-San Francisco · NeuroscienceArgilli Genetics Lab
Emanuela Argilli · San Francisco, California
Research Focus
Dr. Emanuela Argilli's research lab at UCSF focuses on understanding the genetic causes of agenesis of the corpus callosum (ACC), a brain condition linked to various neurodevelopmental disorders like autism, epilepsy, and intellectual disabilities. By studying genetic data from large population samples and engaging in cutting-edge genomic techniques, the lab aims to discover novel genes associated with ACC and explore their implications for brain function and potential treatments. Ultimately, this research could lead to better understanding and interventions for common developmental disorders affecting many individuals worldwide.
geneticsneurodevelopmental disordersagenesis of the corpus callosumgene discoveryanimal modelshuman cell modelsepilepsyintellectual disabilityautism spectrum disorder
Research Aims
3AIM 01Identify novel genetic causes of ACC and related neurodevelopmental disorders.
AIM 02Discover genetic causes of ACC beyond simple mutations by exploring complex genomic regions.
AIM 03Conduct functional analysis of ACC candidate genes to understand their roles in brain signaling and development.
Skills the Lab Values
whole exome sequencing (WES)whole genome sequencing (WGS)animal model studiesgene candidate analysisprotein interaction assaysbiological modelingdata collection and analysiscollaborative research techniques
Output against the department
Publications50bottom 11% of dept.597th of 671
this lab
most publishedleast published
Citations1.8kbottom 11% of dept.599th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.