Duke University · PharmacologyAngiotensin Receptor Drug Development Lab
Laura Michele Wingler · Durham, North Carolina
Research Focus
Dr. Laura Wingler's research focuses on understanding how different drugs affect the angiotensin receptor, which plays a crucial role in regulating blood pressure. The lab investigates specific types of drug interactions with this receptor to improve treatments for cardiovascular diseases like hypertension. The ultimate goal is to design safer and more effective drugs that can target not only angiotensin receptors but also related receptors in the body.
angiotensin receptorG protein-coupled receptorscardiovascular diseasesbiased ligandsdrug development
Research Aims
3AIM 01Determine the functional effects of different angiotensin receptor biased ligands
AIM 02Elucidate the mechanisms of dualsteric angiotensin receptor ligands
AIM 03Develop new biased ligands for better cardiovascular treatments
Skills the Lab Values
cell culturemolecular modelinghigh throughput screeningpharmacological testingbiochemical assays
Output against the department
Publications47bottom 6% of dept.436th of 462
this lab
most publishedleast published
Citations3.4kbottom 26% of dept.342nd of 462
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.