Massachusetts Institute of Technology · EngineeringThe EndoInnovate Lab
Linda G Griffith · Cambridge, Massachusetts
Research Focus
Dr. Linda G. Griffith's lab at MIT focuses on using advanced technologies to better understand and treat women's health issues related to the female reproductive system. They develop innovative models that mimic human tissues, specifically the endometrium, to study diseases like endometriosis and polycystic ovary syndrome (PCOS). By combining insights from biology, engineering, and computational analysis, the lab aims to create personalized medicine solutions that improve clinical outcomes for women suffering from these conditions.
endometriosisgynecologytissue engineeringmicrofluidicspersonalized medicinedrug developmentpreclinical models
Research Aims
3AIM 01Develop robust in vitro models of the human endometrium to study its dynamic functions.
AIM 02Quantify the effects of cell origin and spatial environment on cell identity within the endometrium.
AIM 03Investigate how endothelial cells influence interactions in endometrial models during crucial processes like decidualization.
Skills the Lab Values
microphysiological systems (MPS)tissue engineeringmicrofluidicssingle-cell transcriptomicsspatial transcriptomicsproteomicshydrogel fabricationdata analysisbioinformatics
Output against the department
Publications408top 17% of dept.46th of 278
this lab
most publishedleast published
Citations29ktop 10% of dept.28th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.