The University of Texas Medical Branch at Galveston · BiologyEbola Immune Response Laboratory
Alexander Bukreyev · Galveston, Texas
Research Focus
Dr. Alexander Bukreyev's lab focuses on understanding how the immune system improperly responds to Ebola virus infection. The research aims to identify the molecular mechanisms that cause both excessive inflammation and immune paralysis in affected individuals. By studying these processes, the lab hopes to contribute to the development of effective treatments for Ebola virus and similar viral infections.
Ebola virusimmune responseviral pathogenesistranscriptional regulationposttranslational modificationsimmunologybiotechnology
Research Aims
4AIM 01Investigate the transcriptional changes in immune cells during Ebola virus infection.
AIM 02Examine the posttranscriptional modifications that affect immune responses.
AIM 03Analyze posttranslational modifications contributing to immune dysregulation.
AIM 04Develop models to understand how immune system responses become dysregulated during infection.
Skills the Lab Values
BSL-4 containmentcell cultureRNA sequencingmass spectrometrybioinformaticsgenomic analysismodeling of cell populationsdata integrationstatistical analysis
Output against the department
Publications239top 26% of dept.264th of 1,033
this lab
most publishedleast published
Citations12ktop 29% of dept.301st of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.