Dawlaty Lab

Meelad Dawlaty · Bronx, New York

Albert Einstein College of Medicine · Genetics

Research focus

Dr. Meelad Dawlaty's lab focuses on understanding how specific enzymes, known as Tet enzymes, play a crucial role in the formation of blood cells during embryonic development. They study how these enzymes help regulate the transition of cells from one type to another, specifically from endothelial cells to blood progenitor cells. By exploring the molecular mechanisms behind these processes, the lab aims to inform potential treatments for blood disorders and improve methods for generating blood cells in the lab for clinical applications.

Tet enzymesembryonic hematopoiesisblood cell formationepigeneticsstem cells

Research aims

AIM 01Define the role of Tet enzymes in the specification of hematopoietic cells from endothelial cells during embryonic development.

AIM 02Determine how Tet-mediated DNA demethylation activates hematopoietic gene programs in endothelial cells.

Skills the lab values

PCRcell culturemouse modelsflow cytometryWestern blotgene expression analysisembryonic stem cell derivationmolecular biology techniquesDNA methylation analysis

Output against the department

59publicationsbottom 12% of the department228th of 259

most publishedleast published

9.3kcitationsbottom 49% of the department133rd of 259

most citedleast cited

Career totals from OpenAlex, compared against labs that share a department. Position on each rail is this lab's rank, not its distance from the top: a department runs from one paper to tens of thousands, so rank is the only comparison that stays readable across it.