University of Washington-Seattle Campus · BiologyResilience and Aging Lab
Warren C Ladiges · Seattle, Washington
Research Focus
Dr. Warren Ladiges' lab focuses on understanding how physical resilience impacts healthy aging. By studying how different stressors, like lack of sleep or injury, affect the body, the lab aims to identify factors that help maintain function as individuals age. The research involves using mouse models to explore physiological and molecular responses to stress, which could lead to new therapies enhancing healthy aging in people.
healthy agingphysical resiliencemouse modelsstress responsemolecular pathways
Research Aims
3AIM 01Validate physiological responses to stressors in middle-aged mice
AIM 02Confirm organ-specific effects of stressors through lesion scoring
AIM 03Identify molecular pathways activated by stressors in resilient and susceptible mice
Skills the Lab Values
RNA sequencingimmunohistochemistrymouse behavioral assaysbiostatisticsdigital imagingbiopsy techniquesphenotypic analysispatho-clock analyses
Output against the department
Publications225top 28% of dept.283rd of 1,033
this lab
most publishedleast published
Citations9.6ktop 39% of dept.404th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.