University of Maryland, Baltimore · PharmacologyThe NanoImmune Initiative
Ryan Matthew Pearson · Baltimore, Maryland
Research Focus
Dr. Ryan Matthew Pearson's lab at the University of Maryland Baltimore focuses on developing innovative nanoparticle-based therapies to combat severe inflammation and sepsis. Their research aims to enhance the body's innate immune response using drug-free nanoparticles that can improve survival rates in sepsis through a multimodal approach. This work addresses a critical gap in current sepsis treatments and seeks to offer new, effective solutions to improve patient outcomes.
nanoparticlesimmunotherapysepsisinnate immunityinflammationdrug-free therapiesimmunomodulationtherapeutic windowanimal models
Research Aims
3AIM 01Develop drug-free immunotherapeutic nanoparticles to improve survival in sepsis
AIM 02Investigate the cellular and molecular mechanisms of nanoparticle action
AIM 03Determine the optimal timing and dosing for nanoparticle treatment in sepsis.
Skills the Lab Values
nanoparticle synthesisin vivo modelsflow cytometrycell cultureimmunological assaysdosing and administrationmolecular biology techniquesdata analysis in immunologyanimal handling