University of Virginia-Main Campus · Biomedical EngineeringEpstein Lab
Frederick H Epstein · Charlottesville, Virginia
Research Focus
Dr. Frederick H. Epstein's lab at the University of Virginia focuses on improving heart health through advanced imaging techniques. The lab studies epicardial adipose tissue, which is the fat surrounding the heart, and its impact on conditions like heart failure and coronary microvascular disease. By developing innovative methods to visualize this tissue, researchers aim to uncover new insights into cardiovascular diseases and potential therapeutic approaches.
cardiac MRIepicardial adipose tissueheart failurecoronary microvascular diseasefatty acid compositionSGLT2 inhibitorsexperimental imagingmetabolic diseaseinflammationadaptive therapy
Research Aims
3AIM 01Develop rapid MRI methods to analyze epicardial adipose tissue composition.
AIM 02Investigate the relationship between epicardial adipose tissue and heart failure with preserved ejection fraction.
AIM 03Evaluate the effects of SGLT2 inhibitors on coronary microvascular disease.
Skills the Lab Values
MRI imaging techniques3D imaging methodsfatty acid composition analysismouse model experimentationechocardiographydata analysisbiochemical analysishigh-dimensional imagingbiomarker identification
Output against the department
Publications438top 20% of dept.119th of 595
this lab
most publishedleast published
Citations14ktop 25% of dept.150th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.