University of Chicago · BiologyInfluenza Immunology and Vaccine Design Lab
Sarah Cobey · Chicago, Illinois
Research Focus
Dr. Sarah Cobey's lab at the University of Chicago focuses on understanding immune responses to influenza vaccination. They use computational models to explore how individual differences affect vaccine effectiveness, and the lab aims to improve vaccine design based on these insights. By analyzing immune responses over time, they seek to identify factors that contribute to better protection against influenza infection.
adaptive immunityinfluenza vaccineimmune responsecomputer modelingB and T cell analysis
Research Aims
5AIM 01Investigate the factors influencing individual immune responses to influenza vaccination.
AIM 02Develop statistical and mechanistic models to predict vaccine responses over time.
AIM 03Analyze the role of B and T cell repertoires in shaping vaccine effectiveness.
AIM 04Understand the correlates of protection against influenza infection.
AIM 05Create tools for researchers to study vaccine responses and immunity.
Skills the Lab Values
statistical modelingmachine learningflow cytometrysingle-cell sequencingdata analysis
Output against the department
Publications138top 50% of dept.514th of 1,033
this lab
most publishedleast published
Citations7.1kbottom 49% of dept.527th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.