Columbia University in the City of New York · NeuroscienceElyaman Immunology Lab
Wassim Elyaman · New York, New York
Research Focus
Dr. Wassim Elyaman's research focuses on understanding how the immune system interacts with amyotrophic lateral sclerosis (ALS), a serious neurodegenerative disease that affects motor neurons. His lab investigates specific proteins and antigens that might be involved in the immune response in ALS patients. By characterizing these immune responses, the lab aims to develop more precise immunotherapies that could help slow down disease progression for ALS patients.
ALSimmune responseneurodegenerationT cell therapyantigen presentationmicrogliaT cell receptorsimmunotherapyfrontotemporal dementia
Research Aims
4AIM 01Characterize the immune responses in ALS patients.
AIM 02Identify antigens that activate T cells in the brain of ALS/FTD patients.
AIM 03Map the recognition of these antigens by T cell receptors.
AIM 04Investigate the relationship between immune responses and ALS progression.
Skills the Lab Values
PCRcell cultureflow cytometrymouse modelsRNA sequencingWestern blotimmunohistochemistrybioinformaticsdata analysisprotein purification
Output against the department
Publications124bottom 44% of dept.378th of 671
this lab
most publishedleast published
Citations7.7ktop 48% of dept.323rd of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.