University of Chicago · NeuroscienceGut Microbiota and Parkinson's Research Lab
Tao Xie · Chicago, Illinois
Research Focus
Dr. Tao Xie's lab at the University of Chicago focuses on understanding the relationship between gut bacteria and Parkinson's disease (PD). The research aims to explore how changes in gut microbiota might influence the onset and progression of PD symptoms. The team conducts both cross-sectional and longitudinal studies on diverse patient populations, emphasizing the underrepresented Black community. Through advanced techniques, the lab aims to identify potential biomarkers for diagnosis and novel interventions for treating Parkinson's disease.
gut microbiotaParkinson's diseasedysbiosismultiomicsbiomarkersmachine learninghealth disparitieslongitudinal studiesmetabolomics
Research Aims
5AIM 01Investigate the role of gut dysbiosis in the progression of Parkinson's disease.
AIM 02Collect and analyze microbiota and clinical data from diverse patient demographics.
AIM 03Identify microbiome-based biomarkers predictive of Parkinson's disease progression.
AIM 04Develop targeted interventions leveraging gut microbiota for treating Parkinson's disease.
AIM 05Examine health disparities in Parkinson's disease within Black populations.
Skills the Lab Values
clinical researchmicrobiome analysisdata collectionbioinformaticsmetabolomicsmachine learningparticipant recruitmentfecal sample processingbiopsy techniques
Output against the department
Publications369top 17% of dept.117th of 671
this lab
most publishedleast published
Citations26ktop 15% of dept.103rd of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.