Indiana University-Purdue University-Indianapolis · GeneticsWhite Muscle Lab
Kenneth E White · Indianapolis, Indiana
Research Focus
Dr. Kenneth White's lab focuses on understanding how aging affects muscle and bone health. They are particularly interested in the biochemical pathways that connect muscles, bones, and kidneys, and how these pathways can be influenced by factors like exercise. By investigating the role of specific molecules, such as L-BAIBA and FGF23, the lab aims to identify new therapeutic strategies to improve the quality of life for aging individuals who face issues like sarcopenia and osteoporosis.
muscle agingbone healthFGF23L-BAIBAsarcopeniaosteoporosisinter-tissue signalingkidney functionbiochemical pathwaysexercise physiology
Research Aims
5AIM 01Investigate the role of L-BAIBA in muscle and bone health during aging.
AIM 02Examine how L-BAIBA influences FGF23 production in osteocytes.
AIM 03Explore the interconnected roles of muscle, bone, and kidney in aging.
AIM 04Assess the impact of exercise on L-BAIBA and phosphate balance in older adults.
AIM 05Identify potential therapeutic targets for preventing sarcopenia and osteoporosis.
Skills the Lab Values
cell culturein vitro experimentationanimal modelsmolecular biology techniquesbiochemical assaysdata analysisgenomicsPCRATAC-seqhistology
Output against the department
Publications204top 41% of dept.107th of 259
this lab
most publishedleast published
Citations14ktop 40% of dept.104th of 259
this lab
most citedleast cited
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