Washington University in St Louis · Biomedical EngineeringCervical Cancer Radiation Therapy Lab
Julie Kristina Schwarz · Saint Louis, Missouri
Research Focus
Dr. Julie Kristina Schwarz's lab focuses on improving radiation therapy for cervical cancer by targeting the metabolism of glutamine, an amino acid crucial for cancer cell growth. The research aims to enhance anti-tumor immunity and increase the effectiveness of radiation treatment by combining it with a drug that inhibits glutamine metabolism. Through both laboratory studies and clinical trials, the lab works to develop innovative strategies for treating radiation-resistant cervical cancers.
cervical cancerglutamine metabolismradiation therapyanti-tumor immunityclinical trials
Research Aims
3AIM 01Investigate the impact of glutamine metabolism inhibition on radiation sensitivity in cervical cancer cells.
AIM 02Evaluate the immune response changes when combining glutamine inhibitors with radiation therapy.
AIM 03Test new therapy combinations in preclinical models to support clinical trial advancements.
Skills the Lab Values
cell culture3D co-culture techniquesanimal modelsflow cytometryclinical trial designbiomarker analysisdrug administration protocolstumor microenvironment analysis
Output against the department
Publications336top 27% of dept.161st of 595
this lab
most publishedleast published
Citations7.9ktop 44% of dept.264th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.