Boston University · PhysiologyNeurobiology of Alcohol Consumption Lab
Valentina Sabino · Boston, Massachusetts
Research Focus
Valentina Sabino's lab focuses on understanding the neurobiological mechanisms behind heavy alcohol consumption and its effects on anxiety and pain sensitivity. By studying a neuropeptide called PACAP in the brain's extended amygdala, the lab aims to uncover how chronic alcohol use alters stress responses and contributes to alcohol use disorders. This research has the potential to lead to new treatments for individuals struggling with alcohol dependency.
alcohol use disorderPACAPneurobiologystress responseanxiety behavioranimal modelsalcohol consumptionbrain circuitrytherapeutic agentsneuropeptides
Research Aims
5AIM 01Investigate the role of PACAP in regulating heavy alcohol drinking.
AIM 02Explore the interactions between PACAP and stress neurotransmitter systems.
AIM 03Assess the impact of chronic alcohol exposure on anxiety-like behaviors.
AIM 04Utilize animal models to study the neurocircuitry involved in alcohol consumption.
AIM 05Identify potential therapeutic targets for treating alcohol use disorders.
Skills the Lab Values
animal modelsimmunohistochemistrypharmacological techniquesviral vector manipulationbehavioral assaysmolecular biology techniquesCorticotropin-releasing hormone assaysneurotransmitter analysisdata collection and analysisneural circuit mapping
Output against the department
Publications88bottom 22% of dept.222nd of 286
this lab
most publishedleast published
Citations3.9kbottom 32% of dept.195th of 286
this lab
most citedleast cited
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