University of Minnesota-Twin Cities · BiologyAutoimmune Hemolytic Anemia Research Lab
Steven Gene Friedenberg · Minneapolis, Minnesota
Research Focus
Dr. Steven Gene Friedenberg's lab at the University of Minnesota focuses on understanding autoimmune hemolytic anemia (AIHA), a serious blood disorder that affects both dogs and humans. By studying the genetic and immunological factors in dogs, the lab aims to create a model system that can provide insights into the disease and help in developing new treatments that may benefit human patients as well.
autoimmune hemolytic anemiagenetic risk factorsT cell biologycanine modelimmunotherapy
Research Aims
5AIM 01Investigate the genetic risk factors for autoimmune hemolytic anemia in dogs.
AIM 02Characterize the autoreactive T cell population in predisposed dog breeds.
AIM 03Develop novel immunotherapies based on findings from canine model studies.
AIM 04Lay groundwork for studying autoimmune disorders using canine models.
AIM 05Advance understanding of the immunologic mechanisms underlying AIHA.
Skills the Lab Values
flow cytometryanimal handlingimmunologic assaysDNA sequencingcell culture
Output against the department
Publications2bottom 1% of dept.1,028th of 1,033
this lab
most publishedleast published
Citations0bottom 1% of dept.1,032nd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.