Upstate Medical University · Microbiology & ImmunologyMurphy Neurovirology Lab
Eain A Murphy · Syracuse, New York
Research Focus
Eain Murphy's lab at Upstate Medical University focuses on understanding the link between neurotropic viral infections and Alzheimer's Disease. The research explores how infections by certain herpesviruses might influence the progression of the disease by altering key proteins involved in neurodegeneration. Using advanced 3D brain models, the lab aims to shed light on the biological mechanisms that could lead to new therapeutic strategies for Alzheimer's Disease.
Alzheimer's Diseaseherpesvirusneuroinflammationgene expression3D organoids
Research Aims
3AIM 01Identify viral-dependent changes in host proteins associated with neurodegeneration.
AIM 02Profile the transcriptome of infected cells using novel RNA labeling protocols.
AIM 03Determine the impact of herpesvirus infections on the onset of Alzheimer's Disease in genetic risk factor models.
Skills the Lab Values
cell cultureRNA sequencingsingle cell sequencingimmunohistochemistrymolecular cloning
Output against the department
Publications60bottom 16% of dept.409th of 486
this lab
most publishedleast published
Citations2.5kbottom 15% of dept.414th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.