University at Buffalo · PhysiologyCircadian Cardiac Rhythms Unit
Kedar Kirtikumar Aras · Buffalo, New York
Research Focus
Dr. Kedar Kirtikumar Aras's lab focuses on understanding how the circadian rhythms of the heart affect its susceptibility to dangerous arrhythmias, especially during certain times of the day. The research aims to uncover the mechanisms behind sudden cardiac arrest and explore new treatments to realign the heart's biological clock. This work combines studies on both swine models and human donor hearts, highlighting the potential for novel therapeutic strategies to manage heart health.
cardiac rhythmsarrhythmiassudden cardiac arrestcircadian disruptionpharmacological intervention
Research Aims
3AIM 01Investigate the incidence of arrhythmias during different times of day in swine with chronic heart conditions.
AIM 02Examine the relationship between circadian misalignment and arrhythmia risk in the heart.
AIM 03Validate findings from swine studies using donor human hearts to establish broader implications.
Skills the Lab Values
optical mappingin vivo electrical mappingcardiac surgery techniquesanimal model experimentationdata analysis in physiology
Output against the department
Publications53bottom 8% of dept.263rd of 286
this lab
most publishedleast published
Citations1.4kbottom 6% of dept.269th of 286
this lab
most citedleast cited
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