Baylor College of Medicine · PhysiologyWehrens Lab
Xander H.T. Wehrens · Houston, Texas
Research Focus
Dr. Xander H.T. Wehrens' lab at Baylor College of Medicine focuses on understanding atrial fibrillation, a common heart rhythm disorder. The team investigates the molecular mechanisms that contribute to this condition, including the roles of inflammation and specific signaling pathways that lead to abnormal heart activity. Through innovative models and techniques, their goal is to uncover new strategies for prevention and treatment of atrial fibrillation and related complications.
atrial fibrillationnucleoside diphosphate kinasecalcium signalingpostoperative atrial fibrillationinflammationfibrosisgene therapycardiomyocyte-fibroblast signalingpro-inflammatory cytokinesmicroscopy
Research Aims
3AIM 01Investigate the impact of nucleoside diphosphate kinases on atrial fibrillation development.
AIM 02Study the role of inflammation in postoperative atrial fibrillation.
AIM 03Dissect the signaling pathways between cardiomyocytes and fibroblasts in atrial fibrillation.
Skills the Lab Values
PCRcell culturemouse modelssingle-cell RNA sequencingfluorescence microscopyWestern blotbioinformaticsgene therapy techniqueselectrophysiologyflow cytometry
Output against the department
Publications453top 7% of dept.21st of 286
this lab
most publishedleast published
Citations23ktop 10% of dept.30th of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.