University of Washington-Seattle Campus · EngineeringNance Lab
Elizabeth A Nance · Seattle, Washington
Research Focus
Dr. Elizabeth A Nance's lab at the University of Washington focuses on developing therapies for infants born prematurely, who often face serious neurological challenges. The lab uses advanced techniques in both cultured brain tissues and ferret models to explore how to combine various neuroprotective treatments to improve brain health and development in these vulnerable infants.
premature birthneuroprotectionbrain injurycombinatorial therapiesin vitroferret modelcognitive impairmentinflammationsynaptic changes
Research Aims
5AIM 01Evaluate the efficacy of neurotherapeutics in vitro for brain injury treatment
AIM 02Determine the regional specificity of neuroprotection in the developing brain
AIM 03Develop a combination therapy to optimize neuroprotection in vivo
AIM 04Investigate the role of inflammation in brain injury and recovery
AIM 05Create a preclinical model for future clinical trials in preterm infants.
Skills the Lab Values
cell culturein vivo modelingimmunohistochemistryRNA sequencingbehavioral assessmentdata analysistherapeutic screeningmagnetic resonance imaging (MRI)multi-drug interaction studies
Output against the department
Publications110bottom 24% of dept.211th of 278
this lab
most publishedleast published
Citations5.0kbottom 40% of dept.167th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.