WMCWeill Medical College of Cornell University · Biomedical Engineering
Lipid Metabolism and Alzheimer’s Research Lab
Laura Beth Johnson Mcintire · New York, New York
Research Focus
Dr. Laura Beth Johnson Mcintire's lab focuses on understanding how lipid metabolism changes in the brain due to Alzheimer's disease. They aim to create a detailed atlas of lipid distribution in the brain to help identify key changes that could lead to new biomarkers or therapeutic targets for Alzheimer's. By studying both human brains and mouse models, the lab seeks to connect findings in lipid dysregulation to cognitive decline and disease progression in Alzheimer's disease.
Alzheimer's Diseaselipidomicsneurodegenerative disordersbrain atlaslipid metabolism
Research Aims
5AIM 01Create a comprehensive lipidomics atlas of the brain.
AIM 02Identify biomarkers linked to lipid dysregulation in Alzheimer's disease.
AIM 03Investigate the role of specific genes in lipid metabolism and Alzheimer's pathology.
AIM 04Map the regional distribution of lipids in brain tissues from human and mouse models.
AIM 05Test hypotheses regarding acyl chain remodeling and its impact on Alzheimer's disease.
Skills the Lab Values
lipidomicsanimal modelsimmunohistochemistrygene expression analysisbioinformaticstissue sectioningmass spectrometrymicroscopydata visualization
Output against the department
Publications1bottom 1% of dept.594th of 595
this lab
most publishedleast published
Citations25bottom 2% of dept.586th of 595
this lab
most citedleast cited
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