University of Minnesota-Twin Cities · NeuroscienceThe DBS Optimization Lab
Matthew Douglas Johnson · Minneapolis, Minnesota
Research Focus
Dr. Matthew Douglas Johnson's lab at the University of Minnesota focuses on improving deep brain stimulation (DBS) therapy for Parkinson's disease. The research aims to optimize stimulation settings in order to enhance motor control and address specific symptoms such as bradykinesia, rigidity, tremor, and postural instability. By using advanced technologies like microelectrode arrays and adaptive control algorithms, the lab seeks to develop personalized and responsive therapies for patients.
Deep Brain StimulationParkinson's DiseaseNeural PathwaysMotor ControlElectrophysiology
Research Aims
3AIM 01Investigate how DBS spatiotemporal parameters influence neural activation in the motor control network.
AIM 02Develop algorithms to optimize DBS settings based on patient-specific symptoms.
AIM 03Validate computational models of DBS therapy using real-time electrophysiological data.
Skills the Lab Values
Microelectrode Array RecordingsDeep Brain Stimulation OptimizationData Analysis with Bayesian AlgorithmsHigh-Resolution Anatomical ImagingElectrophysiology Techniques