University of Arkansas for Medical Sciences · PharmacologyRadiation Immunology and Platelet Dynamics Lab
Rupak Pathak · Little Rock, Arkansas
Research Focus
Dr. Rupak Pathak's lab focuses on understanding how platelets interact with the immune system, especially after exposure to harmful radiation. This research is vital for developing new therapies to protect individuals from immune disorders caused by nuclear events. The lab aims to find ways to improve immune response and protect against organ damage by examining platelet behaviors and their interactions with immune cells.
radiation immunologyplatelet-leukocyte interactionimmune dysregulationplatelet-derived microparticlesradiation protection
Research Aims
5AIM 01Investigate how platelets contribute to immune dysregulation after radiation exposure.
AIM 02Test the effectiveness of platelet receptor interactions in mediating immune responses to radiation.
AIM 03Explore the role of platelet-derived microparticles in inflammatory processes following ionizing radiation exposure.
AIM 04Evaluate strategies for administering exogenous GPIb to mitigate immune dysregulation.
AIM 05Develop new therapeutic approaches to prevent organ damage due to radiation exposure.
Skills the Lab Values
cell culturemouse modelsimmunohistochemistryflow cytometryRNA extraction
Output against the department
Publications98bottom 24% of dept.349th of 462
this lab
most publishedleast published
Citations1.3kbottom 6% of dept.433rd of 462
this lab
most citedleast cited
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