University of California-San Diego · BiologySubramani Biogenesis Lab
Suresh Subramani · La Jolla, California
Research Focus
Dr. Suresh Subramani's lab at UC San Diego primarily investigates the mechanisms of peroxisome biogenesis, focusing on how these essential organelles are formed in cells. By utilizing yeast models, the lab aims to uncover key genes and proteins involved in the creation and regulation of peroxisomes, as well as the communication between peroxisomes and other cellular structures. This research not only enhances our understanding of cellular biology but also has implications for diagnosing and treating peroxisome biogenesis disorders in humans.
peroxisome biogenesisyeast modelsmolecular biologycellular communicationlipid transport
Research Aims
3AIM 01Identify genes involved in de novo peroxisome biogenesis.
AIM 02Elucidate interactions between lipid regulators and peroxisome biogenesis proteins.
AIM 03Investigate the impact of mitochondrial signaling on peroxisome proliferation.
Skills the Lab Values
high-throughput screening (HTS)genetic screeningfunctional protein studiescell culture techniquesmicroscopyprotein analysismolecular cloningyeast genetics
Output against the department
Publications306top 18% of dept.187th of 1,033
this lab
most publishedleast published
Citations25ktop 15% of dept.160th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.