Harvard University · ChemistryThe Antibiotic Innovation Hub
Andrew G Myers · Cambridge, Massachusetts
Research Focus
Dr. Andrew G. Myers' lab at Harvard University focuses on developing new antibiotics to combat the growing problem of antibiotic resistance, particularly against multi-drug resistant bacteria. The research involves synthesizing innovative antibiotic compounds and studying their mechanisms of action to combat pathogens that pose significant threats to public health. This work aims to deliver novel antibiotic options that can effectively treat serious bacterial infections that have become resistant to existing drugs.
antibioticsantibiotic resistanceGram-negative bacterialincosamidesmulti-drug resistant pathogenssynthesismechanism of actioncryo-EM imagingpharmacokineticsnatural products
Research Aims
5AIM 01Develop new antibiotics to target multi-drug resistant bacterial pathogens.
AIM 02Synthesize and evaluate novel lincosamide analogs for improved efficacy against bacteria.
AIM 03Explore mechanisms of action of lead compounds using cryo-EM imaging.
AIM 04Investigate the synthetic pathways to create a diverse set of antibiotic candidates.
AIM 05Assess pharmacokinetic and pharmacodynamic properties of new antibiotic candidates.
Skills the Lab Values
synthetic organic chemistryantibiotic synthesisbiological assayscryogenic electron microscopy (cryo-EM)in vitro testingpharmacodynamic studiesanalytical chemistry techniquesmolecular modelinglaboratory safety practicesdata analysis
Output against the department
Publications345top 32% of dept.69th of 216
this lab
most publishedleast published
Citations13ktop 40% of dept.86th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.