Michigan State University · PharmacologyRockwell Lab
Cheryl Elizabeth Rockwell · East Lansing, Michigan
Research Focus
Dr. Cheryl Rockwell's lab focuses on understanding how dietary additives, specifically tert-butylhydroquinone (tBHQ), affect the immune response to influenza. They aim to uncover the mechanisms behind how tBHQ impairs T cell function, which is crucial for fighting viral infections and achieving effective vaccinations. This research could lead to better predictions about how certain substances in our diets might influence our immunity to diseases.
influenzaT cellsimmune responsefood additivesNrf2virusCD4 T cellsCD8 T cellsimmunological memory
Research Aims
3AIM 01Investigate how tBHQ affects Th1 differentiation in T cells.
AIM 02Determine the underlying mechanisms of impaired T cell function due to tBHQ.
AIM 03Assess the effects of tBHQ on both primary and memory immune responses to influenza.
Skills the Lab Values
cell cultureanimal modelsflow cytometrycytokine analysismolecular cloningWestern blotRNA extractionqPCRin vivo immunologydata analysis with R
Output against the department
Publications116bottom 32% of dept.312th of 462
this lab
most publishedleast published
Citations2.1kbottom 15% of dept.395th of 462
this lab
most citedleast cited
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