Vanderbilt University · ChemistryThe ImmunoHarvest Lab
Brian O Bachmann · Nashville, Tennessee
Research Focus
Professor Brian O Bachmann's lab at Vanderbilt University focuses on discovering new cancer therapies from natural products. They explore how these compounds can trigger immune responses against cancer cells and develop innovative methods to analyze these effects at the single-cell level. The lab aims to uncover how cell injury signals can enhance the immune system's ability to fight tumors, providing insights that may lead to more effective cancer treatments.
natural product discoverycancer immunotherapysingle cell analysisimmune responsecell death signaling
Research Aims
3AIM 01Discover new natural products that induce immunogenic cell death in cancer cells.
AIM 02Characterize the immune signaling pathways activated by these natural products.
AIM 03Validate the therapeutic potential of these compounds through advanced cell assays.
Skills the Lab Values
flow cytometrycell culturechemical biologyimmune cell profilinghigh throughput screening
Output against the department
Publications122bottom 26% of dept.159th of 216
this lab
most publishedleast published
Citations4.3kbottom 32% of dept.147th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.