Harvard University · Mathematics & StatisticsHIV Clinical Trials and Data Analysis Lab
Michael David Hughes · Cambridge, Massachusetts
Research Focus
Dr. Michael David Hughes leads a research lab at Harvard School of Public Health focused on advanced statistical methodologies and data management to improve clinical trials for HIV/AIDS and associated infections. The lab supports the AIDS Clinical Trials Group, which aims to develop novel interventions, enhance treatment strategies, and improve diagnostic approaches for individuals living with HIV and co-infections like tuberculosis and hepatitis B. Their work is critical in shaping international research standards and treatment protocols that ultimately enhance public health outcomes.
HIVclinical trialsdata managementbiostatisticstuberculosishepatitis Bco-infectionsdata analysispublic healthclinical therapeutics
Research Aims
5AIM 01Evaluate novel interventions for HIV infection.
AIM 02Identify strategies to reduce HIV reservoirs.
AIM 03Improve diagnosis and treatment of tuberculosis in HIV co-infected patients.
AIM 04Enhance prevention and treatment of hepatitis B co-infection.
AIM 05Support the international research agenda of the ACTG.
Skills the Lab Values
statistical analysisdata management systemsclinical trial designbiostatisticsdata quality assuranceepidemiological methodsdata visualizationregulatory complianceSPSSR programming
Output against the department
Publications479top 17% of dept.22nd of 131
this lab
most publishedleast published
Citations25ktop 21% of dept.27th of 131
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.