Florida International University · BiologyAlzheimer's Therapeutics Lab
Kyung Bo Kim · Miami, Florida
Research Focus
Dr. Kyung Bo Kim's research lab at Florida International University is focused on developing new treatments for Alzheimer's disease (AD). They are specifically exploring a novel class of drugs that inhibit the immunoproteasome, which may help improve cognitive deficits associated with AD without relying on the traditional targets of amyloid-beta and tau proteins. The lab aims to identify and characterize macrocyclic peptide compounds that can effectively cross the blood-brain barrier and demonstrate prolonged activity in the brain.
Alzheimer's Diseaseimmunoproteasomemacrocyclic peptidesdrug developmentcognitive deficits
Research Aims
3AIM 01Prepare macrocyclic peptide epoxyketones for testing their properties
AIM 02Characterize the in vivo properties of the peptide compounds
AIM 03Verify the efficacy and mechanism of action of the lead drug candidate in mouse models of AD
Skills the Lab Values
peptide synthesisin vivo studiesmouse modelsdrug efficacy testinganalytical chemistry
Output against the department
Publications91bottom 30% of dept.720th of 1,033
this lab
most publishedleast published
Citations3.8kbottom 29% of dept.733rd of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.