Cornell University · EngineeringVascular Cognition Lab
Chris B Schaffer · Ithaca, New York
Research Focus
Dr. Chris B. Schaffer's lab at Cornell University focuses on understanding how blood flow in the brain affects cognitive functions related to Alzheimer's Disease (AD) and other related dementias. The research investigates how improving blood circulation can enhance memory and correct neural activity imbalances in mouse models. This work aims to uncover mechanisms that could potentially lead to new therapies for cognitive symptoms in AD.
Alzheimer's Diseasecerebral blood flowneural activitymemory functionvascular health
Research Aims
3AIM 01Examine how increased cerebral blood flow improves neuronal oxygenation and metabolism.
AIM 02Investigate the correction of activity imbalances in neurons due to improved blood flow.
AIM 03Test the normalization of hippocampal activity involved in memory formation.
Skills the Lab Values
mouse modelsimmunohistochemistryelectrophysiologybehavioral assaysfluorescence microscopy
Output against the department
Publications215top 44% of dept.121st of 278
this lab
most publishedleast published
Citations14ktop 27% of dept.75th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.