University of Colorado Boulder · GeneticsGrotzinger Lab
Andrew David Grotzinger · Boulder, Colorado
Research Focus
Dr. Andrew David Grotzinger's lab at the University of Colorado focuses on understanding the genetic underpinnings of Major Depressive Disorder (MDD). Utilizing advanced genomic techniques, the lab aims to identify distinct genetic subtypes of MDD and their associations with various biological pathways. Their research has the potential to improve diagnosis and treatment options for individuals suffering from depression, offering insights tailored to different patient profiles.
Major Depressive Disordergenetic subtypesGenome-Wide Association StudyGenomic SEMdrug repurposing
Research Aims
5AIM 01Identify genetically distinguishable subgroups within Major Depressive Disorder.
AIM 02Analyze differences in genetic architecture related to onset age and socioeconomic status.
AIM 03Characterize biological pathways related to subtype-specific risk.
AIM 04Evaluate genetic overlaps with other psychiatric disorders and cognitive traits.
AIM 05Investigate potential pharmacological interventions for MDD subtypes.
Skills the Lab Values
GWASGenomic Structural Equation Modelingdata analysis in Rbioinformaticsgene expression analysis
Output against the department
Publications149bottom 48% of dept.134th of 259
this lab
most publishedleast published
Citations7.3kbottom 39% of dept.157th of 259
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.