Georgia State University · BiologyXu Lab
Jianliang Xu · Atlanta, Georgia
Research Focus
Dr. Jianliang Xu's lab focuses on developing innovative treatments for HIV using nanobodies, which are smaller and more versatile than traditional antibodies. The lab aims to create nanobodies that can target multiple sites on the HIV virus, potentially improving treatment effectiveness and simplifying administration. Their work could lead to breakthrough therapies that enhance the fight against AIDS and offer new hope for patients worldwide.
HIVnanobodiesbroadly neutralizing antibodiesAIDS therapyantibody engineering
Research Aims
3AIM 01Develop novel nanobodies targeting HIV Env protein sites.
AIM 02Characterize the mechanisms of action of engineered nanobodies.
AIM 03Enhance nanobody effectiveness through rational design strategies.
Skills the Lab Values
phage displayantibody characterizationneutralization assaysbioinformaticsstructural analysisX-ray crystallographyelectron microscopy
Output against the department
Publications569top 5% of dept.56th of 1,033
this lab
most publishedleast published
Citations9.8ktop 39% of dept.399th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.