Icahn School of Medicine at Mount Sinai · NeuroscienceLaboratory for Photochemical Neural Control
Graham Ellis-Davies · New York, New York
Research Focus
Dr. Graham Ellis-Davies' lab focuses on developing innovative optical technologies that allow for precise control over neuronal function, both in laboratory settings and living organisms. By creating advanced photochemical tools, the lab enables researchers to manipulate neurotransmitter activity and neuron signaling processes, unveiling new insights into cellular physiology. The work is grounded in collaboration with physiologists, ensuring that the technologies meet real biological challenges.
photochemical controlneuronal functioncaged neurotransmittersoptical methodspharmacologysignal transductionin vivo studiescell physiologyphotoswitchable probestwo-photon excitation
Research Aims
5AIM 01Develop new photochemical tools for optical control of neurons.
AIM 02Create multi-color photoactuation methods.
AIM 03Design caged compounds for two-photon excitation.
AIM 04Investigate photocontrol of membrane excitability.
AIM 05Collaborate with physiologists to enhance tool utility.
Skills the Lab Values
optogeneticsphotochemistrycaged compound synthesisin vitro neuron culturein vivo imagingtwo-photon microscopyfluorescence spectroscopydrug formulationcollaborative research techniquesneurophysiology
Output against the department
Publications157top 48% of dept.318th of 671
this lab
most publishedleast published
Citations15ktop 27% of dept.180th of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.