University of Florida · BiologyPotassium Channels and Viral Immunity Lab
Daniel Swale · Gainesville, Florida
Research Focus
Dr. Daniel Swale's lab at the University of Florida studies how potassium channels influence the immune response to viruses. By examining these channels in various organisms, including insects and mammals, the research aims to uncover how potassium levels affect antiviral responses and could inform new therapeutic strategies. The lab will explore the connections between ion channels, immune function, and viral replication, contributing to a better understanding of viral infections and potential interventions.
potassium channelsviral replicationantiviral immunityRNA interferenceion homeostasisoxidative metabolismDengue virusimmune responsecellular metabolismcardiac activity
Research Aims
3AIM 01Investigate how KATP channels influence circulatory homeostasis during viral infection.
AIM 02Determine the interaction between KATP channels and the antiviral RNAi pathway.
AIM 03Examine the role of reactive oxygen species in regulating antiviral immune pathways.
Skills the Lab Values
PCRgene silencingsmall RNA sequencingtransgenic organism designcell cultureexperiment designdata analysisimmunological assaysbioinformaticscomparative biology
Output against the department
Publications74bottom 21% of dept.814th of 1,033
this lab
most publishedleast published
Citations1.3kbottom 8% of dept.950th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.