Stanford University · BiophysicsFeng Mitochondrial Lab
Liang Feng · Stanford, California
Research Focus
The research lab led by Liang Feng at Stanford University focuses on understanding how mitochondrial membrane transport systems influence cellular energy production and signaling. By investigating the mechanisms of calcium transport and other critical processes within mitochondria, they aim to uncover how these systems contribute to normal physiology and diseases such as metabolic, cardiovascular, and neurodegenerative disorders. This work may also lead to new therapeutic strategies targeting these transport systems.
mitochondrial functionmembrane transportcalcium signalingmetabolismdisease mechanismstherapeutic targetstransport proteinscellular energeticspyruvate transport
Research Aims
5AIM 01Elucidate the transport mechanisms of mitochondrial calcium uniporter.
AIM 02Investigate the regulation and function of the sodium-calcium exchanger NCLX.
AIM 03Decipher the role of the mitochondrial pyruvate carrier in energy metabolism.
AIM 04Assess the impact of small molecules on transport activity.
AIM 05Explore the implications of mitochondrial transport dysregulation in diseases.
Skills the Lab Values
biochemical assaysprotein purificationcell culturefluorescence microscopymolecular cloningspectrophotometrychromatographyelectrophysiologycomputational modeling
Output against the department
Publications152top 40% of dept.4th of 10
this lab
most publishedleast published
Citations7.8ktop 50% of dept.5th of 10
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.