University of California-San Diego · ChemistryJones Proteomics Lab
Lisa M Jones · La Jolla, California
Research Focus
Lisa M Jones's lab at UC San Diego studies proteins in complex environments that better mimic natural cellular conditions. They develop techniques to understand how proteins interact, fold, and aggregate, which can lead to new therapeutic strategies. Their work is particularly focused on improving methods used in mass spectrometry to study protein structure and function in cellular models and in diseases.
protein structureprotein interactionsmass spectrometryprotein aggregationprotein misfoldingin vivo studiesthree-dimensional models
Research Aims
5AIM 01Develop new methods to study protein structure in complex environments.
AIM 02Identify protein interactions involved in misfolding and aggregation.
AIM 03Apply mass spectrometry techniques to understand protein folding dynamics.
AIM 04Expand current methodologies into ex vivo tissue models.
AIM 05Design novel therapeutics targeting protein misfolding.
Skills the Lab Values
mass spectrometryprotein footprintingcell cultureC. elegans modelsbiological modelingoxidative modification techniquesdata analysis in protein studieshydroxyl radical methodsprotein-ligand interactions
Output against the department
Publications147bottom 36% of dept.138th of 216
this lab
most publishedleast published
Citations13ktop 41% of dept.89th of 216
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.