Johns Hopkins University · Biomedical EngineeringThe Glioblastoma Insight Lab
Shanshan Jiang · Baltimore, Maryland
Research Focus
Dr. Shanshan Jiang's lab at Johns Hopkins University focuses on improving the diagnosis and treatment monitoring of glioblastoma, a highly aggressive brain tumor. The research combines innovative liquid biopsy techniques, analyzing circulating tumor DNA, with advanced MRI imaging to provide real-time insights into how well patients are responding to treatment. This work aims to develop non-invasive methods that could spare many patients from unnecessary surgeries and lead to more personalized treatment strategies.
glioblastomaliquid biopsycirculating tumor DNAMRIdeep learningcancer monitoringtumor recurrencepersonalized medicinenon-invasive diagnostics
Research Aims
3AIM 01Integrate ctDNA and CSF-tDNA levels with APT MRI metrics in glioblastoma therapy.
AIM 02Evaluate the effectiveness of combined rtDNA/APT indices in detecting tumor recurrence.
AIM 03Create a deep learning model to assess prognosis using rtDNA and MRI data.
Skills the Lab Values
DNA extractionbiofluid samplingPCRmagnetic resonance imaging (MRI)data analysis with Pythondeep learning frameworksbiostatisticsgenetic marker analysisclinical trial protocols
Output against the department
Publications136bottom 28% of dept.428th of 595
this lab
most publishedleast published
Citations3.9kbottom 30% of dept.415th of 595
this lab
most citedleast cited
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