University of California-Davis · BiologyCanine Osteosarcoma Research Lab
Robert B Rebhun · Davis, California
Research Focus
Dr. Robert B Rebhun's lab at UC Davis focuses on studying osteosarcoma in dogs, aiming to improve the understanding of this cancer to eventually enhance treatment for both dogs and humans. By investigating the tumor microenvironment and immune responses in naturally occurring cases, the lab seeks to establish better clinical outcomes for dogs and provide valuable insights for human cancer therapies. This work integrates veterinary science with comparative oncology to bridge gaps in translational research.
osteosarcomacomparative oncologytumor microenvironmentimmune profilingcanine modelchemoresistanceclinical trialsmolecular characterizationgenomics
Research Aims
5AIM 01Determine natural disease progression and outcomes in dogs with osteosarcoma
AIM 02Characterize the tumor microenvironment and immune landscape in canine osteosarcoma
AIM 03Establish biologically based outcome assessments for canine osteosarcoma trials
AIM 04Enhance the design of canine trials to inform human osteosarcoma treatments
AIM 05Translate findings from canine studies to improve outcomes for human patients.
Skills the Lab Values
cell culturesurvival analysisimmune characterizationbiomarker discoverydata analysissurgical techniquesclinical trial designgenomic sequencingstatistical modeling
Output against the department
Publications137bottom 49% of dept.520th of 1,033
this lab
most publishedleast published
Citations3.6kbottom 28% of dept.747th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.