Ohio State University-Main Campus · BiochemistryMihaylova Metabolism Lab
Maria M. Mihaylova · Columbus, Ohio
Research Focus
Dr. Maria M. Mihaylova's research lab at Ohio State University focuses on understanding how aging affects cancer metabolism. Her team studies the metabolic changes in tumors and their surrounding environments as people age, with the goal of discovering new insights into cancer initiation and progression. By using advanced techniques to analyze single cells, they aim to uncover how diets and microbiome metabolites influence these processes, potentially transforming how we treat cancers in older individuals.
agingcancer metabolismtumor microenvironmentsingle cell technologymetabolic heterogeneitydietary factorsmicrobiome effectstumor progressionmetabolic liabilities
Research Aims
5AIM 01Investigate how age-related metabolic changes contribute to cancer development.
AIM 02Characterize metabolic alterations in tumors and their microenvironments over time.
AIM 03Assess the effects of dietary nutrients on cancer progression.
AIM 04Examine the impact of microbiome-derived metabolites on tumor growth.
AIM 05Identify potential therapeutic targets by studying metabolic vulnerabilities.
Skills the Lab Values
single cell analysiscell cultureanimal modelsflow cytometrymetabolic assaysgenomic analysisdata visualizationnutrient manipulationimmunohistochemistry
Output against the department
Publications53bottom 8% of dept.368th of 402
this lab
most publishedleast published
Citations16ktop 30% of dept.119th of 402
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.