Yale University · GeneticsSkin Repair and Regeneration Lab
Valentina Greco · New Haven, Connecticut
Research Focus
Dr. Valentina Greco's lab at Yale University focuses on understanding how skin tissue repairs itself after injury. They use advanced imaging techniques to observe and manipulate skin cells in live mice, allowing them to see how different types of cells cooperate during the healing process. The research aims to improve our understanding of wound healing, which is critical for treating chronic wounds and preventing skin cancer.
skin repairfibroblastsepithelial cellslive imagingstem cellscell signalingwound healingmouse modelscancer mutationstissue homeostasis
Research Aims
5AIM 01Define how genetically diverse epithelial cells respond to skin injury.
AIM 02Examine the role of fibroblasts during skin repair processes.
AIM 03Investigate the signaling pathways that coordinate stem cell behaviors in the skin.
AIM 04Understand the molecular mechanisms regulating stem cell differentiation in live animals.
AIM 05Characterize the dynamics of calcium signaling in skin cell populations.
Skills the Lab Values
intravital microscopygenetic manipulationpharmacological interventionssingle-cell RNA sequencingcalcium imagingcell culturemouse modelsdata analysisimmunofluorescencetranscriptional profiling
Output against the department
Publications118bottom 38% of dept.161st of 259
this lab
most publishedleast published
Citations7.4kbottom 41% of dept.154th of 259
this lab
most citedleast cited
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