Northeastern University · EngineeringNiedre Lab
Mark Jonathan Niedre · Boston, Massachusetts
Research Focus
Mark Jonathan Niedre's lab focuses on developing innovative techniques to monitor circulating tumor cells (CTCs) in real-time within living models. By using a novel non-invasive optical method, they aim to study how CTCs influence metastasis in various cancers, particularly in response to treatments like radiation. This research could lead to significant advancements in understanding cancer progression and improving therapeutic approaches.
circulating tumor cellsmetastasisoptical monitoringradiation therapynon-invasive methodscancer researchtumor dynamicsanti-inflammatory therapymouse models
Research Aims
4AIM 01Develop a wearable device for continuous monitoring of circulating tumor cells in mice.
AIM 02Investigate the dynamic changes in circulating tumor cell numbers during cancer progression.
AIM 03Assess the impact of radiation therapy on circulating tumor cell dynamics in a medulloblastoma model.
AIM 04Explore the effects of anti-inflammatory drugs on metastasis through circulating tumor cells.
Skills the Lab Values
diffuse in vivo flow cytometryoptical signal processinganimal surgerymouse modelsfluorescence imagingdata collectionexperimental designsoftware for data analysisvivo imaging techniques
Output against the department
Publications1bottom 1% of dept.276th of 278
this lab
most publishedleast published
Citations0bottom 1% of dept.277th of 278
this lab
most citedleast cited
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