The University of Texas Health Science Center at San Antonio · GeneticsInnovative Pediatric Cancer Lab
Raushan Kurmasheva · San Antonio, Texas
Research Focus
Dr. Raushan Kurmasheva's lab focuses on improving cancer treatment for children and adolescents through innovative research using patient-derived tumor models. They aim to discover new drugs and therapies that are more effective and less toxic than current treatments, leveraging models that reflect the unique genetic characteristics of high-risk pediatric tumors. Their work is crucial for developing targeted therapies that can significantly enhance survival rates and reduce long-term health complications for young cancer patients.
pediatric cancersarcomahepatoblastomapatient-derived xenograftsdrug developmentimmuno-oncologychemotherapynanoparticle drug deliverydrug combinationsclinical trials
Research Aims
5AIM 01Identify novel agents for treating pediatric high-risk sarcomas and liver cancers.
AIM 02Utilize patient-derived xenografts to model pediatric cancers for drug testing.
AIM 03Test combinations of conventional therapies and new drug agents.
AIM 04Explore the genetic diversity of pediatric tumors through innovative preclinical testing.
AIM 05Develop less toxic treatment options that improve survival rates in children with cancer.
Skills the Lab Values
patient-derived xenograft modelsdrug formulationmolecular characterizationchemotherapy drug testingnanoparticle delivery systemsimmunotherapy testingclinical trial designepigenetic analysisdata analysis using Pythoncell culture techniques
Output against the department
Publications403top 17% of dept.43rd of 259
this lab
most publishedleast published
Citations3.6kbottom 19% of dept.211th of 259
this lab
most citedleast cited
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