UGUniversity of Georgia · Physiology
Kanthasamy Lab
Arthi Kanthasamy · Athens, Georgia
Research Focus
Dr. Arthi Kanthasamy's research lab focuses on understanding how neuroinflammation contributes to Parkinson's disease and related disorders. The lab studies a specific protein, called 'ALKBH5', which plays a role in how immune cells in the brain respond to nerve injury. By investigating the mechanisms of inflammation and cellular signaling processes, the lab aims to develop new therapeutic strategies to treat neurodegenerative diseases.
Parkinson's diseaseneuroinflammationmicrogliaalpha-synucleinepitranscriptomicsALKBH5Fyn-PKC signalingcytokineschemokines
Research Aims
3AIM 01Characterize the role of ALKBH5 in microglial activation during neuroinflammation
AIM 02Determine the impact of Fyn-PKC signaling on ALKBH5 function in immune cells
AIM 03Evaluate the therapeutic potential of targeting the Fyn-PKC-ALKBH5 axis in models of Parkinson's disease
Skills the Lab Values
cell cultureanimal modelsWestern blotRNA sequencingproteomicsimmunofluorescenceflow cytometrydata analysissignal transduction pathways
Output against the department
Publications200top 33% of dept.94th of 286
this lab
most publishedleast published
Citations16ktop 19% of dept.53rd of 286
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.