University of Pennsylvania · Biomedical EngineeringCherenkov Imaging Lab
Timothy C. Zhu · Philadelphia, Pennsylvania
Research Focus
Dr. Timothy C. Zhu's lab at the University of Pennsylvania focuses on improving cancer treatment through advanced imaging techniques. The lab is developing Cherenkov imaging, which uses light emitted from tissue during radiation therapy to create real-time maps of the radiation dose delivered to patients' skin. This innovative approach aims to enhance the precision of total skin electron therapy (TSET) for patients suffering from conditions like mycosis fungoides, ensuring that they receive the correct dose and improving treatment outcomes.
Cherenkov imagingtotal skin electron therapyradiation therapydosimetryreal-time imagingcancer treatmentclinical trialsoptical properties3D surface imaging
Research Aims
5AIM 01Develop Cherenkov imaging as a verification tool for total skin electron therapy.
AIM 02Quantify corrections needed for accurate Cherenkov signal measurements.
AIM 03Evaluate dosimetry accuracy using various detection methods during radiation therapy.
AIM 04Assess actual skin dose distribution using 3D skin anatomy mapping.
AIM 05Conduct a clinical trial to validate Cherenkov imaging in real-time patient treatment monitoring.
Skills the Lab Values
3D surface imagingradiation dosimetryclinical trial designoptical imaging techniquesMonte Carlo simulationssignal processingdata analysis in clinical researchpatient assessment methodscollaborative interdisciplinary research
Output against the department
Publications445top 20% of dept.118th of 595
this lab
most publishedleast published
Citations8.3ktop 41% of dept.243rd of 595
this lab
most citedleast cited
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