Washington University in St Louis · Biomedical EngineeringThe Cardiac Insight Lab
Jie Zheng · Saint Louis, Missouri
Research Focus
Dr. Jie Zheng's lab focuses on advancing cardiac imaging techniques, particularly using magnetic resonance imaging (MRI) to assess how much oxygen the heart muscles extract from the blood. They develop innovative methods that are non-invasive and do not expose patients to harmful radiation, making them safer and potentially more available than existing techniques like PET scans. The lab's research not only aims to improve diagnostic capabilities for heart diseases but also to provide insights into treatment responses for various cardiac conditions.
cardiac imagingoxygen extractionMRIdeep learningheart diseasenon-invasive imagingcardiomyopathy
Research Aims
5AIM 01Develop a novel MRI method for measuring myocardial oxygen extraction fraction.
AIM 02Validate the MRI method using animal models with induced coronary artery disease.
AIM 03Compare the new MRI method to PET imaging in patients with heart disease.
AIM 04Assess the effectiveness of the method in various cardiac conditions, including cardiomyopathies.
AIM 05Establish protocols for regular, non-invasive mOEF measurements in clinical settings.
Skills the Lab Values
MRI acquisition techniquesdeep learning for image processinganimal models in cardiovascular researchclinical trial designdata analysis in medical imagingpatient recruitment and assessmentcardiovascular physiologycontrast agent development
Output against the department
Publications464top 18% of dept.107th of 595
this lab
most publishedleast published
Citations28ktop 11% of dept.64th of 595
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.