WMCWeill Medical College of Cornell University · Microbiology & Immunology
HIV Immunology and Antibody Research Lab
John P Moore · New York, New York
Research Focus
Dr. John P. Moore's lab focuses on understanding how the immune system can effectively combat HIV-1, the virus that causes AIDS. By studying broadly neutralizing antibodies (bNAbs), the lab aims to improve both vaccine strategies and treatments for HIV-1 infection. The research involves innovative methods to analyze antibody behavior and viral interactions to enhance our knowledge of immunity against HIV-1.
HIV-1broadly neutralizing antibodiesvaccine developmentviral escapeimmunization strategies
Research Aims
3AIM 01Analyze the binding properties of broadly neutralizing antibodies related to immunization
AIM 02Determine the relationship between bNAb breadth and its binding characteristics
AIM 03Investigate how viral fitness affects resistance to neutralizing antibodies
Skills the Lab Values
antibody binding assayssurface plasmon resonanceviral particle productioncell culture techniquesmolecular cloningdata analysis using computational toolsimmunological assaysanimal models of infection
Output against the department
Publications570top 4% of dept.20th of 486
this lab
most publishedleast published
Citations56ktop 3% of dept.17th of 486
this lab
most citedleast cited
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