University of Michigan-Ann Arbor · Microbiology & ImmunologyMoore Lab
Bethany B. Moore · Ann Arbor, Michigan
Research Focus
Bethany B. Moore's lab at the University of Michigan focuses on understanding how the immune system interacts with lung cells during injury and fibrosis. They study the role of specific immune and structural cells in managing lung health, especially how these interactions can influence infections and fibrosis. The lab aims to develop targeted therapies for lung diseases that arise from chronic inflammation and to improve the immune responses in fibrotic lungs.
immune crosstalklung injuryfibrosismacrophage-targeted therapiesEpithelial cellsmyeloid cellsbacterial infectionsprostaglandinnanoparticles
Research Aims
4AIM 01Investigate how HB-EGF regulates fibrosis and interacts with myeloid cells.
AIM 02Explore mechanisms of impaired immunity against gram-positive bacteria in fibrotic lungs.
AIM 03Develop targeted delivery methods for COX inhibitors and EP2 antagonists using nanoparticles.
AIM 04Examine the role of TLR9 in structural cells on the immune response in lung infections post-influenza.
Skills the Lab Values
cell culturemouse modelsimmunological assaysRNA sequencingnanoparticle synthesisflow cytometryWestern blottingPCRlive-cell imaging
Output against the department
Publications422top 8% of dept.39th of 486
this lab
most publishedleast published
Citations26ktop 13% of dept.65th of 486
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.