University of Illinois Urbana-Champaign · EngineeringHan Lab
Bumsoo Han · Champaign, Illinois
Research Focus
Dr. Bumsoo Han's lab focuses on developing new treatment strategies for pancreatic ductal adenocarcinoma (PDAC) by altering the tumor's surrounding environment, known as the stroma. The researchers are investigating the role of the coagulation system in the tumor microenvironment and how targeting specific components can enhance drug delivery and combat resistance. By understanding these interactions, the lab aims to improve therapeutic outcomes for patients with pancreatic cancer.
pancreatic cancertumor microenvironmentcoagulationdrug deliverychemoresistancetumor-associated macrophagescancer-associated fibroblastsimmunosuppression
Research Aims
2AIM 01Determine the role of the coagulation targets in the PDAC tumor microenvironment.
AIM 02Evaluate the pharmacological inhibition of coagulation targets using patient-derived PDAC models.
Skills the Lab Values
animal modelsdrug delivery systemsbiomimeticscell culturemolecular signalingin vivo testingpharmacological inhibitionextracellular matrix analysis
Output against the department
Publications169bottom 42% of dept.160th of 278
this lab
most publishedleast published
Citations3.0kbottom 23% of dept.214th of 278
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.