Icahn School of Medicine at Mount Sinai · NeuroscienceSalton Neurobiology Lab
Stephen R Salton · New York, New York
Research Focus
Dr. Stephen Salton's lab at the Icahn School of Medicine focuses on understanding the connections between Alzheimer's Disease and Major Depressive Disorder, two serious brain conditions that often occur together. They study a protein called VGF and its associated peptides, which may be crucial in regulating both diseases. Their research involves using mouse models to test new ways of delivering VGF-derived peptides to see if they can improve brain health and cognitive function.
Alzheimer's DiseaseMajor Depressive DisorderVGFneuropeptidesmouse models
Research Aims
3AIM 01Investigate how VGF interacts with different receptors in the brain.
AIM 02Assess the role of the RPH3A protein in Alzheimer’s and depression.
AIM 03Explore how VGF-derived peptides can be used to reduce cognitive decline and pathology.
Skills the Lab Values
molecular biology techniquesanimal behavior assessmentsgene expression analysisbiochemical assaysintranasal drug delivery
Output against the department
Publications110bottom 38% of dept.413th of 671
this lab
most publishedleast published
Citations5.1kbottom 37% of dept.422nd of 671
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.