Carnegie Mellon University · BiologyBasal Ganglia Restoration Lab
Aryn Hilary Gittis · Pittsburgh, Pennsylvania
Research Focus
Dr. Aryn Hilary Gittis' lab at Carnegie-Mellon University focuses on understanding and restoring brain function in diseases like Parkinson's Disease. They employ advanced techniques to target specific neurons in a brain region called the basal ganglia, exploring how these interventions can alleviate both motor and non-motor symptoms associated with the disease. The research aims to develop innovative therapies that not only treat symptoms but also promote long-term recovery of brain function.
Parkinson's DiseaseDeep Brain StimulationBasal GangliaOptogeneticsNeural CircuitsTherapeutic PlasticityNeuronal DysfunctionBehavior RescueMouse Models
Research Aims
3AIM 01Map the neural pathways necessary for persistent behavioral rescue in Parkinson's Disease.
AIM 02Identify the short-term and long-term physiological effects of interventions in the globus pallidus.
AIM 03Assess the efficacy of targeted interventions during different stages of dopamine depletion.
Skills the Lab Values
OptogeneticsElectrophysiologyAnimal Behavior AssessmentNeuronal ImagingDeep Brain Stimulation TechniquesMouse ModelsData Analysis in NeuroscienceSurgical Techniques in Animal StudiesNeural Pathway Mapping
Output against the department
Publications84bottom 26% of dept.759th of 1,033
this lab
most publishedleast published
Citations3.2kbottom 24% of dept.789th of 1,033
this lab
most citedleast cited
Career totals from OpenAlex, compared against labs that share a department. A department spans everything from one paper to tens of thousands, so bar heights are on a log scale — otherwise the largest lab would flatten every other bar to a line.