University of Minnesota-Twin Cities · PharmacologyLaboratory for Maternal Epilepsy Research
Angela K Birnbaum · Minneapolis, Minnesota
Research Focus
Dr. Angela K. Birnbaum's lab focuses on understanding how antiseizure medications affect pregnant women and their breastfeeding infants. By using advanced modeling techniques, the lab aims to determine the best drug dosages that are both safe for the developing fetus and effective for the mother's epilepsy treatment. Their research is critical for improving health outcomes for women with epilepsy during pregnancy and lactation.
antiseizure medicationsphysiological-based pharmacokineticspregnancybreastfeedingepilepsycongenital malformationsneurodevelopmental outcomesdrug exposureprecision medicine
Research Aims
5AIM 01Investigate the pharmacokinetics of antiseizure medications in pregnant women.
AIM 02Evaluate drug exposure to infants during breastfeeding.
AIM 03Assess the risk of congenital malformations from antiseizure medications.
AIM 04Develop precision medicine approaches for dosing during pregnancy and lactation.
AIM 05Combine clinical and basic science data to enhance understanding of drug safety.
Skills the Lab Values
physiological-based pharmacokinetic modelingdata analysisclinical study designin vitro techniquesanimal modelsdrug concentration measurementpatient cohort studiespharmacodynamicspharmacokinetics
Output against the department
Publications180bottom 49% of dept.232nd of 462
this lab
most publishedleast published
Citations4.3kbottom 32% of dept.314th of 462
this lab
most citedleast cited
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